How long does it take for 100 mg of Seroquel to leave your system?

Medicine · Middle School · Tue Nov 03 2020

Answered on


The elimination half-life of a medication like Seroquel (quetiapine) can vary from person to person and is typically around 6 to 7 hours for the immediate-release formulation and longer for the extended-release formulation. However, it's important to note that the complete clearance of a medication from the system can take several half-lives.

For example, after one elimination half-life, roughly 50% of the drug is eliminated, after two half-lives approximately 75% is eliminated, after three half-lives about 87.5% is eliminated, and so on. Most medications are considered to be eliminated from the system after about five half-lives, which would equate to approximately 30-35 hours for immediate-release Seroquel.

It's important to consult with a healthcare professional or pharmacist for personalized information regarding the clearance of a specific medication like Seroquel, as individual factors can influence the metabolism and elimination of drugs, affecting how long it stays in your system. These factors can include liver function, kidney function, age, other medications being taken concurrently, and individual differences in metabolism.

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