A higher dose of local anesthetic agent was inadvertently 
administered through Intravenous route. Which of the 
following system is most likely involved in the toxic effect? 
a. Cardiovascular system 
b. Immune system 
c. Gastrointestinal system 
d. Respiratory system 

Medicine ยท Wed Jul 13 2022

Answered on

In the given scenario, if a higher dose of a local anesthetic agent was inadvertently administered through the intravenous route, the cardiovascular system is most likely to be involved in the toxic effect.


Local anesthetic agents are used to block pain sensation in a specific area of the body. When administered in correct doses and routes, they are generally safe. However, if a higher dose is mistakenly administered through the intravenous route, it can lead to systemic toxicity.

The cardiovascular system is responsible for circulating blood throughout the body, delivering oxygen and nutrients to various tissues and organs. When a local anesthetic agent enters the bloodstream in high concentrations, it can affect the cardiovascular system by causing vasodilation (widening of blood vessels), which can lead to decreased blood pressure. This can result in reduced oxygen supply to vital organs, such as the brain and heart, and potentially lead to serious complications.

Symptoms of cardiovascular toxicity from a local anesthetic overdose may include dizziness, lightheadedness, decreased heart rate, low blood pressure, and in severe cases, cardiac arrest.

It is essential to be cautious and follow proper administration guidelines to prevent such incidents and ensure patient safety. In case of an accidental overdose, immediate medical intervention is necessary to manage the toxic effects on the cardiovascular system.

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