Neural tube defect is due to: 
a. Valproate                          b. Phenytoin 
c. Diazoxide                         d. None of these 

Medicine ยท Wed Jul 13 2022

Answered on

Neural tube defects are a type of birth defect that affects the development of the brain and spinal cord. They occur during the early stages of pregnancy when the neural tube, which eventually becomes the brain and spinal cord, fails to close completely. The exact cause of neural tube defects is not known, but there are several factors that can increase the risk.


One of the factors that can increase the risk of neural tube defects is the use of certain medications during pregnancy. In the given options, both Valproate (option a) and Phenytoin (option b) are medications that have been associated with an increased risk of neural tube defects. Valproate is commonly used to treat epilepsy and bipolar disorder, while Phenytoin is also used to treat epilepsy. However, it's important to note that not all women who take these medications will have babies with neural tube defects, and the risks and benefits should be discussed with a healthcare professional.

On the other hand, Diazoxide (option c) is not known to be associated with an increased risk of neural tube defects. So, the correct answer to the question is d. None of these.

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