A person with a small intestine that has villi but a reduced number of microvilli would be expected to experience decreased nutrient absorption.

Yes, that is correct. The small intestine is a key site for nutrient absorption in the digestive system. Inside the small intestine, the lining is covered with numerous tiny, finger-like projections called villi. Each villus further has many smaller, hair-like extensions called microvilli which form what is known as the brush border. The role of both structures is to increase the surface area for absorption dramatically.

When a person has a reduced number of microvilli, the overall surface area available for nutrient absorption is decreased. Microvilli are integral to a process called the final digestion where enzymes attached to the membrane of the microvilli break down nutrients into their smallest absorbable units. They are also directly responsible for the absorption of nutrients after they have been digested. Therefore, a decrease in the number of microvilli may lead to less efficient absorption of nutrients such as carbohydrates, proteins, and fats as well as vitamins and minerals. This can result in nutritional deficiencies and contribute to conditions such as malabsorption syndrome.