why are organisms with similar genetic sequences also likely to have similar protein configurations?

Biology · Middle School · Thu Feb 04 2021

Answered on

Organisms with similar genetic sequences are likely to have similar protein configurations because the sequence of nucleotides in DNA determines the sequence of amino acids in proteins, which in turn determines the protein's structure and function.

Here's how the process works:

1. DNA Structure : DNA is composed of four nucleotides: adenine (A), thymine (T), cytosine (C), and guanine (G). The sequence of these nucleotides encodes genetic information.

2. Transcription: During transcription, a segment of DNA is used as a template to create messenger RNA (mRNA). The mRNA sequence is complementary to the DNA template and is similarly made up of nucleotides, except that uracil (U) replaces thymine.

3. Translation : The mRNA then travels to a ribosome, where it is translated into a protein. This translation is done by reading the nucleotides in sets of three, known as codons. Each codon specifies a particular amino acid.

4. Amino Acid Sequence: The sequence of amino acids in a protein is determined by the sequence of codons in the mRNA, which in turn is determined by the original DNA sequence.

5. Protein Folding: Proteins fold into complex three-dimensional shapes that are determined by the interactions among their amino acids. These interactions are influenced by the properties of the individual amino acids, such as charge and hydrophobicity.

6. Protein Function: The final configuration (conformation) of the protein determines its function. Proteins with similar amino acid sequences often fold into similar shapes and thus have similar functions.

Therefore, if two organisms have similar genetic sequences, the proteins encoded by these sequences will have similar amino acid sequences. Since the amino acid sequence dictates the protein's configuration, these proteins are likely to have similar shapes and functions.