Which statement about control of glycogen metabolism is INCORRECT? Which statement about control of glycogen metabolism is INCORRECT? Glycogen phosphorylase is activated by phosphorylation. Glucagon signals glycogen breakdown in liver. Epinephrine signals glycogen breakdown in muscle. Glycogen synthase is phosphorylated at only one site.
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The incorrect statement about control of glycogen metabolism is: "Glycogen synthase is phosphorylated at only one site." This statement is not true because glycogen synthase, the enzyme responsible for glycogen synthesis, can be phosphorylated at multiple sites, which affects its activity. Phosphorylation typically turns off glycogen synthase's activity which would prevent glycogen from being synthesized when the body doesn't need it (e.g., when energy levels are high). Multiple kinases can phosphorylate different sites on glycogen synthase which leads to a sophisticated regulation of its activity.