Which of the following statements is true regarding DNA replication? A. The 5' to 3' orientation of the new strand will depend upon where it is in the replication bubble relative to the position where replication first starts. B. The new strand is the opposite of the template strand. C. The new strand is an exact complement to the template strand. D. The new strand is exactly the same as the template strand.
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These options are true about DNA.
A. The 5' to 3' orientation of the new strand will depend upon where it is in the replication bubble relative to the position where replication first starts.
DNA is always synthesized in the 5'-to-3' direction, meaning that nucleotides are added only to the 3' end of the growing strand.
B. The new strand is the opposite of the template strand.
Coding or “Sense strand” runs in a 5'- 3' direction, opposite to the template strand. As the RNAP uses the template strand to transcribe the mRNA, the other strand will be the sense strand that will form a complementary strand to that of the template.
C. The new strand is an exact complement to the template strand.
The coding, or non-template, strand is the DNA strand complementary to the template strand; it has the same sequence (except for T for U substitutions) as the mRNA.