What information can not be obtained from the sequence of a gene?A) Relationship between two species.B) Effects of a mutation on gene function.C) Whether the gene is methylated.D) Amino acid sequence of a gene.
Biology · High School · Thu Feb 04 2021
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C) Whether the gene is methylated.
Methylation is a form of DNA modification that involves the addition of a methyl group to the DNA molecule, usually at specific cytosine residues in the context of a CpG dinucleotide in higher eukaryotes. Methylation can affect gene expression and can have a role in gene regulation. The sequence of a gene itself, typically represented as a string of nucleotides (adenine [A], thymine [T], cytosine [C], and guanine [G]), does not provide information about the methylation status of the gene. DNA sequencing methods usually do not detect methyl groups; instead, specialized techniques such as bisulfite sequencing or whole genome bisulfite sequencing are required to determine methylation patterns.