In dna replication, the leading strand _________

Biology · High School · Sun Jan 24 2021

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In dna replication, the leading strand  continuously synthesis strand . 

One new strand, which runs 5' to 3' towards the replication fork, is the easy one. This strand is made continuously, because the DNA polymerase is moving in the same direction as the replication fork. This continuously synthesized strand is called the leading strand.

DNA synthesis always occurs in the 5'-->3' because chain growth results from the formation of a phosphodiester bond between the 3' OH of a growing strand and α-phosphate of a dNTP. This makes options B and D wrong. The DNA strand in which DNA synthesis in 5'-->3' direction proceeds continuously in the same direction as replication fork movement is called leading strand. This makes option A correct. The lagging strand synthesis occurs in the 5'-->3' direction but proceeds in the opposite direction from the movement of the replication fork. This is done by synthesizing a new primer every few hundred bases on the second parental strand. Each of these primers is elongated in the 5'-->3' direction and form discontinuous segments called Okazaki fragments.